Ardalani, H. (2016). The ethnopharmacological review of medicinal plants in uses hypertension treatment in Iranian complementary medicine. Journal of Herbal Drugs
(An International Journal on Medicinal Herbs), 7(1), 9-13.
Hamidreza Ardalani. "The ethnopharmacological review of medicinal plants in uses hypertension treatment in Iranian complementary medicine". Journal of Herbal Drugs
(An International Journal on Medicinal Herbs), 7, 1, 2016, 9-13.
Ardalani, H. (2016). 'The ethnopharmacological review of medicinal plants in uses hypertension treatment in Iranian complementary medicine', Journal of Herbal Drugs
(An International Journal on Medicinal Herbs), 7(1), pp. 9-13.
Ardalani, H. The ethnopharmacological review of medicinal plants in uses hypertension treatment in Iranian complementary medicine. Journal of Herbal Drugs
(An International Journal on Medicinal Herbs), 2016; 7(1): 9-13.
The ethnopharmacological review of medicinal plants in uses hypertension treatment in Iranian complementary medicine
Department of Horticultural Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran
Abstract
Background & Aim: One of the most common diseases in the world, especially among Iranian people, is high blood pressure which can cause many cardiovascular disorders such as heart attack. The disease is often associated with other diseases such as diabetes and hyperlipidemia. Methyldopa and captopril are the most common drugs among several medications used to control blood pressure in Iran. Nowadays, herbal medicines are very prevalent because medicinal plants have least of the side effects. Various herbals are used in the Iranian traditional medicine to improve hypertension, but among them, barberry, olive leaf, garlic, celery, sumac and hibiscus are the most prevalent. Experimental: In this paper, the most herbs in uses in treatment of hypertension were studied and these effects of natural products on these plants were clarified. Results & Discussion: The results indicate that these plants and their phenolic compounds can be used as an alternative or supplement to chemical medicines used to control blood pressure. Industrial and practical recommendations: There is suggestion for pharmaceuticals and food industrials to use of these herbs for improve new methodology in herbal drugs production.
مطالعه گیاهان دارویی مرسوم در کنترل فشار خون در طب مکمل ایرانی
Authors [Persian]
حمیدرضا اردلانی
گروه علوم باغبانی، واحد علوم و تحقیقات، دانشگاه آزاد اسلامی، تهران، ایران
Abstract [Persian]
مقدمه و هدف:یکی از مهمترین بیماری های رایج در جهان بالاخص در ایران، فشار خون است که مشکلات بسیاری همچون حملات و سکته های قلبی را بوجود می آورد. بیماری فشار خون اغلب با بیماری های دیگری نظیر دیابت و چربی خون همراه است. داروی متیل دوپا و کاپتوپریل پرمصرف ترین داروی کنترل فشار خون در ایران است. امروزه گیاهان دارویی به دلیل داشتن حداقل عوارض جانبی بسیار قابل توجه هستند. گیاهان دارویی بسیاری در طب سنتی ایران جهت کنترل فشار خون استفاده می شود که می توان از آنها به زرشک، برگ زیتون، سیر، کرفس، سماق و چای ترش اشاره کرد روش تحقیق: در این مطالعه به گیاهان پرمصرف در در درمان و کنترل فشارخون و مواد موثره آنها و همچنین مطالعات بالینی آنها پرداخته می شود.نتایج و بحث: نتایج بدست آمده از مطالعه نشان می دهد که گیاهان دارویی مذکور می تواند به عنوان مکمل همراه با داروهای شیمیایی اثرات بسیار بهتری داشته باشد و از عوارض جانبی مصرف بیش از حد داروهای شیمیایی در کنترل فشار خون بکاهد. توصیه کاربردی/ صنعتی: همچنین در آخر به صنایع دارویی و غذایی توصیه می شود روش های نوین در فرمولاسیون گیاهان دارویی و ساخت داروهای گیاهی نوترکیب را بکار گیرند.
Keywords [Persian]
اتنوفارماکولوژی، فشار خون، گیاهان دارویی، طب مکمل، ایران
References
Ajiboye, T.O., Salawu, N.A., Yakubu, M.T., Oladiji, A.T., Akanji, M.A., Okogun, J.I. 2011. Antioxidant and drug detoxification potentials of Hibiscus sabdariffa anthocyanin extract. Drug and chemical toxicology, 34: 109-115.
Ali, M., Al-Qattan, K., Al-Enezi, F., Khanafer, R., Mustafa, T. 2000. Effect of allicin from garlic powder on serum lipids and blood pressure in rats fed with a high cholesterol diet. Prostaglandins, leukotrienes and essential fatty acids, 62: 253-259.
Appel, L.J., Champagne, C.M., Harsha, D.W., Cooper, L.S., Obarzanek, E., Elmer, P.J., Stevens, V.J., Vollmer, W.M., Lin, P.-H., Svetkey, L.P. 2003. Effects of comprehensive lifestyle modification on blood pressure control: main results of the PREMIER clinical trial. Journal of the American Medical Association.
Beevers, G., Lip, G.Y., O'Brien, E. 2001. ABC of hypertension: Blood pressure measurement: Part II—Conventional sphygmomanometry: technique of auscultatory blood pressure measurement. British Medical Journal, 322: 1043.
Cicero, A.F., Ertek, S. 2009. Metabolic and cardiovascular effects of berberine: from preclinical evidences to clinical trial results. Clinical Lipidology, 4: 553-563.
Collaboration, B.P.L.T.T. 2000. Effects of ACE inhibitors, calcium antagonists, and other blood-pressure-lowering drugs: results of prospectively designed overviews of randomised trials. The Lancet, 356: 1955-1964.
Eidi, A., Eidi, M., Esmaeili, E. 2006. Antidiabetic effect of garlic (Allium sativum L.) in normal and streptozotocin-induced diabetic rats. Phytomedicine, 13: 624-629.
Faraji, M.H., Tarkhani, A.H. 1999. The effect of sour tea (Hibiscus sabdariffa) on essential hypertension. Journal of Ethnopharmacology, 65: 231-236.
Fatehi‐Hassanabad, Z., Jafarzadeh, M., Tarhini, A., Fatehi, M. 2005. The antihypertensive and vasodilator effects of aqueous extract from Berberis vulgaris fruit on hypertensive rats. Phytotherapy Research, 19: 222-225.
Fazal, S.S., Singla, R.K. 2012. Review on the pharmacognostical & pharmacological characterization of Apium graveolens Linn. Indo Global Journal of Pharmaceutical Sciences, 2: 36-42.
Fehri, B., Aiache, J., Memmi, A., Korbi, S., Yacoubi, M., Mrad, S., Lamaison, J., 1993. [Hypotension, hypoglycemia and hypouricemia recorded after repeated administration of aqueous leaf extract of Olea europaea L.]. Journal de pharmacie de Belgique, 49: 101-108.
Herrera-Arellano, A., Flores-Romero, S., Chavez-Soto, M., Tortoriello, J. 2004. Effectiveness and tolerability of a standardized extract from Hibiscus sabdariffa in patients with mild to moderate hypertension: a controlled and randomized clinical trial. Phytomedicine, 11: 375-382.
Hong, Y., Hui, S.-C., Chan, T.-Y., Hou, J.-Y. 2002. Effect of berberine on regression of pressure-overload induced cardiac hypertrophy in rats. The American journal of Chinese medicine, 30: 589-599.
Huang, C.L., Sumpio, B.E. 2008. Olive oil, the mediterranean diet, and cardiovascular health. Journal of the American College of Surgeons, 207: 407-416.
Imanshahidi, M., Hosseinzadeh, H. 2008. Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine. Phytotherapy research, 22: 999-1012.
Kimbaris, A.C., Siatis, N.G., Daferera, D.J., Tarantilis, P.A., Pappas, C.S., Polissiou, M.G. 2006. Comparison of distillation and ultrasound-assisted extraction methods for the isolation of sensitive aroma compounds from garlic (Allium sativum). Ultrasonics sonochemistry, 13: 54-60.
Koch, H.P., Lawson, L.D. 1996. Garlic: the science and therapeutic application of Allium sativum L. and related species. baltimore, Maryland: Williams & Wilkins xv, 329p. ISBN.
Leng, G.C., Lee, A.J., FOWKERS, F.G.R., WHITEMAN, M., Dunbar, J., Housley, E., Ruckley, C.V. 1996. Incidence, natural history and cardiovascular events in symptomatic and asymptomatic peripheral arterial disease in the general population. International journal of epidemiology, 25: 1172-1181.
Lloyd-Jones, D.M., Evans, J.C., Levy, D., 2005. Hypertension in adults across the age spectrum: current outcomes and control in the community. Journal of the American Medical Association, 294: 466-472.
MacMahon, S., Peto, R., Collins, R., Godwin, J., Cutler, J., Sorlie, P., Abbott, R., Neaton, J., Dyer, A., Stamler, J. 1990. Blood pressure, stroke, and coronary heart disease: part 1, prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias. The Lancet, 335: 765-774.
Mansi, K., Abushoffa, A.M., Disi, A., Aburjai, T. 2009. Hypolipidemic effects of seed extract of celery (Apium graveolens) in rats. Pharmacognosy magazine, 5: 301.
Moghadam, M.H., Imenshahidi, M., Mohajeri, S.A. 2013. Antihypertensive effect of celery seed on rat blood pressure in chronic administration. Journal of medicinal food, 16: 558-563.
Momin, R.A., Nair, M.G. 2001. Mosquitocidal, nematicidal, and antifungal compounds from Apium graveolens L. seeds. Journal of agricultural and food chemistry, 49: 142-145.
Mozaffari-Khosravi, H., Jalali-Khanabadi, B., Afkhami-Ardekani, M., Fatehi, F., Noori-Shadkam, M. 2009. The effects of sour tea (Hibiscus sabdariffa) on hypertension in patients with type II diabetes. Journal of human hypertension, 23: 48-54.
Onyenekwe, P., Ajani, E., Ameh, D., Gamaniel, K. 1999. Antihypertensive effect of roselle (Hibiscus sabdariffa) calyx infusion in spontaneously hypertensive rats and a comparison of its toxicity with that in Wistar rats. Cell Biochemistry and Function, 17: 199-206.
Perrinjaquet‐Moccetti, T., Busjahn, A., Schmidlin, C., Schmidt, A., Bradl, B., Aydogan, C. 2008. Food supplementation with an olive (Olea europaea L.) leaf extract reduces blood pressure in borderline hypertensive monozygotic twins. Phytotherapy Research, 22: 1239-1242.
Reinhart, K.M., Coleman, C.I., Teevan, C., Vachhani, P., White, C.M. 2008. Effects of garlic on blood pressure in patients with and without systolic hypertension: a meta-analysis. Annals of Pharmacotherapy, 42: 1766-1771.
Susalit, E., Agus, N., Effendi, I., Tjandrawinata, R.R., Nofiarny, D., Perrinjaquet-Moccetti, T., Verbruggen, M. 2011. Olive (Olea europaea) leaf extract effective in patients with stage-1 hypertension: comparison with Captopril. Phytomedicine, 18: 251-258.
Tekol, Y., 2007. The medieval physician Avicenna used an herbal calcium channel blocker, Taxus baccata L. Phytotherapy Research, 21: 701-702.
Thomson, M., Ali, M. 2003. Garlic [Allium sativum]: a review of its potential use as an anti-cancer agent. Current cancer drug targets, 3: 67-81.
Wahabi, H., Alansary, L., Al-Sabban, A., Glasziuo, P. 2010. The effectiveness of Hibiscus sabdariffa in the treatment of hypertension: a systematic review. Phytomedicine, 17: 83-86.
Wargovich, M.J., 1987. Diallyl sulfide, a flavor component of garlic (Allium sativum), inhibits dimethyihydrazine-induced colon cancer. Carcinogenesis, 8: 487-489.
Zhang, Q., Zhou, M.M., Chen, P.L., Cao, Y.Y., Tan, X.L., 2011. Optimization of Ultrasonic‐Assisted Enzymatic Hydrolysis for the Extraction of Luteolin and Apigenin from Celery. Journal of food science, 76: C680-C685.
Top