Assessment of secondary metabolites: in vitro antiarthritic and antihemolytic potential of various extracts of garlic

Document Type: Original article

Authors

Department of Life Sciences, ITM University, Gwalior

Abstract

Background & Aim: Allium sativum commonly known as garlic is an herb used over years to prevent from various ailments such as cardiovascular diseases, cognitive disorders and also enhances the immune system. The aim of the present study is to study the in vitro antiarthritic and antihemolytic potential of garlic in aqueous and methanolic extracts. Fourier transform infrared spectroscopy was performed to study the presence of functional groups. Experimental: The study involved detection of primary and secondary metabolites in allium sativum i.e garlic. In vitro antiarthritic and heat induced haemolytic assaywas evaluated so that it could be used against haemolytic diseases such as malaria, swine flu etc. FTIR spectra were performed to detect the presence of functional groups.
Results: Natural products due to their immense bioactivity, finds applications against various diseases without having side effects. Recommended applications/industrie: This herb is very easily accessible and is edible it can be used as a pharmaceutical agent. Bioactive constituents can be isolated and explored for further activity.

Keywords


Article Title [Persian]

بررسی متابولیتهای ثانویه، تاثیر ضد ورم مفاصل و ضد همولیتیک عصاره های مختلف سیر در شرایط آزمایشگاهی

Authors [Persian]

  • سونیا جهری
  • نصیر خان
  • ساریتا تیواری
  • لاویه شاکیاوار
Department of Life Sciences, ITM University, Gwalior
Abstract [Persian]

Background & Aim: Allium sativum commonly known as garlic is an herb used over years to prevent from various ailments such as cardiovascular diseases, cognitive disorders and also enhances the immune system. The aim of the present study is to study the in vitro antiarthritic and antihemolytic potential of garlic in aqueous and methanolic extracts. Fourier transform infrared spectroscopy was performed to study the presence of functional groups. Experimental: The study involved detection of primary and secondary metabolites in allium sativum i.e garlic. In vitro antiarthritic and heat induced haemolytic assaywas evaluated so that it could be used against haemolytic diseases such as malaria, swine flu etc. FTIR spectra were performed to detect the presence of functional groups. Results: Natural products due to their immense bioactivity, finds applications against various diseases without having side effects. Recommended applications/industrie: This herb is very easily accessible and is edible it can be used as a pharmaceutical agent. Bioactive constituents can be isolated and explored for further activity.

Keywords [Persian]

  • Allium sativum
  • FTIR
  • ضد ورم مفاصل
  • ضد همولیتیک
  • شرایط آزمایشگاهی
  • متابولیتهای ثانویه
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