Anti-inflammatory activity of leaf extract of Solanum anomalum

Document Type: Original article

Authors

1 Department of pharmacology and toxicology, Faculty of pharmacy, University of Uyo, Uyo, Nigeria

2 Department of Physiology, Faculty of Basic Medical Sciences, University of Uyo, Uyo, Nigeria

3 Department of Pharmacology and Therapeutics, College of Medicine, Evans Enwerem University, Orlu Campus, Imo State

Abstract

Background & Aim: Solanum anomalum Thonn. ex Schumach. (family Solanaceae) is a shrub growing up to 2 metres tall. The edible fruits are gathered from the wild and consumed locally and the leaves are used locally in the treatment of various diseases. Evaluation of anti-inflammatory activity of leaf extract of Solanum anomalum was carried out to ascertain its uses in traditional medicine.
Experimental: The crude leaf extract (70 – 210 mg/kg) of Solanum anomalum was investigated for anti-inflammatory activity using various experimental models; carragenin, egg albumin and xylene induced oedema.
Results: The extract (70 -210 mg/kg) caused a significant (p
Recommended applications/industries: The plant, Breynia nivosa, possesses antiinflammatory property which can be exploited in the treatment of inflammatory diseases.

Keywords


Article Title [Persian]

فعالیت ضد التهابی عصاره برگ Solanum anomalum

Authors [Persian]

  • جود اکوکون 1
  • کوفره دیویز 2
  • لوییس آمازو 3
  • امام یوموه 1
1 Department of pharmacology and toxicology, Faculty of pharmacy, University of Uyo, Uyo, Nigeria
2 Department of Physiology, Faculty of Basic Medical Sciences, University of Uyo, Uyo, Nigeria
3 Department of Pharmacology and Therapeutics, College of Medicine, Evans Enwerem University, Orlu Campus, Imo State
Abstract [Persian]

Background & Aim: Solanum anomalum Thonn. ex Schumach. (family Solanaceae) is a shrub growing up to 2 metres tall. The edible fruits are gathered from the wild and consumed locally and the leaves are used locally in the treatment of various diseases. Evaluation of anti-inflammatory activity of leaf extract of Solanum anomalum was carried out to ascertain its uses in traditional medicine.
Experimental: The crude leaf extract (70 – 210 mg/kg) of Solanum anomalum was investigated for anti-inflammatory activity using various experimental models; carragenin, egg albumin and xylene induced oedema.
Results: The extract (70 -210 mg/kg) caused a significant (p
Recommended applications/industries: The plant, Breynia nivosa, possesses antiinflammatory property which can be exploited in the treatment of inflammatory diseases.

Keywords [Persian]

  • Solanum anomalum
  • ضد التهاب
  • آماس
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