Antimicrobial Effects of Zataria multiflora Essential Oils on Acinetobacter Strains Isolated from Clinical Specimens

Document Type : Original article


1 Department of Obstetrics and Fetal Health Research Center, Zabol University of Medical Sciences, Zabol, Iran;

2 Zabol Medicinal Plant Research Center, Zabol University of Medical Sciences, Zabol, Iran;

3 Department of Biology, Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman, Iran;

4 Center of Agricultural Biotechnology, University of Zabol, Zabol, Iran;


Background & Aim: The aim of this study was to investigate the antimicrobial effects of Zataria multiflora against some Acinetobacter baumannii strains isolated from clinical samples.
Experimental: Twelve strains of Acinetobacter baumannii were isolated from referred patients in Zabol hospital. Essential oil of Zataria multifloraspecies was extracted using Clevenger device. Minimum Inhibitory Concentration (MIC) and Minimum Bacterial Concentration (MBC) of essential oil on mentioned bacteria were determined using micro dilution broth method at six different concentrations.
Results: The results of this study showed that the lowest inhibitory concentration of essential oil against bacteria was 0.31 mg/ml, and only one strain of bacteria was inhibited. However, the highest inhibitory concentration was estimated 10 mg/ml.
Recommended applications/industries: The results showed that the antimicrobial effects increased with increasing in essential oil concentration and the essence showed good antimicrobial activity even at low concentrations. With the use of essential oil of Zataria multiflora against bacterial pathogens, a good antimicrobial agent can be obtained without any side effects. 


Article Title [فارسی]

بررسی فعالیت ضد میکروبی اسانس آویشن شیرازی بر روی اسینتو باکتر بومانی جدا شده از نمونه های بالینی

Authors [فارسی]

  • خدیجه رضایی کیخواهی 1
  • غلامرضا باقری 2
  • مهدی حسن شاهیان 3
  • سعیده سعیدی 4
1 مرکز تحقیقاتی مامایی، دانشگاه علوم پزشکی زابل، زابل، ایران
2 مرکز تحقیقات گیاهان دارویی زابل، دانشگاه علوم پزشکی زابل، زابل، ایران
3 گروه زیست شناسی، دانشکده علوم، دانشگاه شهید باهنر کرمان، کرمان، ایران
4 مرکز تحقیقات بیوتکنولوژی کشاورزی، دانشگاه زابل، زابل، ایران
Abstract [فارسی]

مقدمه و هدف: هدف از این مطالعه بررسی فعالیت ضد میکروبی اسانس آویشن شیرازی بر روی اسینتو باکتر بومانی جدا شده از نمونه های بالینی است.
روش تحقیق: دوازده سویه اسینتو باکتر بومانی از بیمارستان های شهرستان زابل جداسازی شد. اسانس آویشن شیرازی با استفاده از دستگاه کلونجر بدست آمد، در نهایت حداقل غلظت مهار کنندگی و حداقل غلظت کشندگی اسانس در برابر باکتریهای ذکرشده با روش میکرودایلوشن تعیین گردید.
نتایج و بحث: نتایج حاصل از این مطالعه نشان داد که کمترین غلظت مهار کنندگی در برابر باکتری ها برابر با 31/0 میلی گرم بر میلی لیتر است و تنها یک سویه از باکتری در این غلظت مهار شده است. بیشترین غلظت مهار کننندگی برابر با 10 میلی گرم بر میلی لیتر بوده و یک سویه نیز در این غلظت مهار شده است.
توصیه کاربردی و صنعتی: نتایج نشان داد که اسانس با افزایش غلظت اثرات ضد میکروبی آن افزایش پیدا می کند، اسانس آویشن فعالیت ضد میکروبی خوبی حتی در غلظت های پایین از خود نشان داد. با کاربرد اسانس آویشن شیرازی علیه باکتری های بیماریزا می توان به یک ماده ضد میکروبی خوب بدون اثر جانبی دست پیدا کرد.

Keywords [فارسی]

  • آویشن شیرازی
  • اسانس
  • فعالیت ضد میکروبی
  • اسینتو باکتر بومانی
  • حداقل غلظت مهار کنندگی
  • حداقل غلظت کشندگی
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